NEW PUBLICATION: Direct comparison of single peak and gradient chromatographic methods for routine analysis of surfactants in biopharmaceuticals

New Publication: Direct comparison of single peak and gradient chromatographic methods for routine analysis of surfactants in biopharmaceuticals

Publication Highlights:

• Single-peak methods are fast and simple, but may overlook degradation.
• Gradient LC with CAD/MS detection provide deeper insights into degradation, while remaining time-efficient (e.g., 5.5 min for polysorbates, 11 min for poloxamer 188).
• LC-CAD quantification of surfactants is more complex than expected—especially when surfactant degradation occurs.